We independently evaluate all of our recommendations. If you click on links we provide, we may receive compensation. Shopping Beauty Skincare Glycolic Acid: The Anti-Aging Ingredient Derms Can't Stop Raving About The "DL" on this powerhouse ingredient and how to incorporate it into your beauty routine. By Kristin Granero Kristin Granero Kristin Granero is a lifestyle writer, content creator, and digital media expert residing in New York City. When she's not interviewing experts or test-driving the latest products, she can be found exploring new museum exhibits, volunteering for her local animal rescue, or scouring the five boroughs (and beyond!) in search of the best guacamole. Highlights: * 3+ years writing Style, Beauty, Health, and Home content for Real Simple * Has held positions at and/or contributed to a wide range of lifestyle and entertainment publishers, including Seventeen, Cosmopolitan, Women's Health, Shape, Self, Glamour, HBO, TODAY, NBC, Discovery, Yahoo, and beyond * Experience includes copywriting, web production, social media strategy, and email marketing Real Simple's Editorial Guidelines Updated on March 19, 2024 Medically reviewed by Hadley King, MD Medically reviewed by Hadley King, MD Hadley King, MD is a board-certified dermatologist who specializes in medical and cosmetic dermatology. She is also a Clinical Instructor of Dermatology at the Weill Medical College of Cornell University.Dr. King is a highly sought after dermatologist in New York City, where she has been treating patients for almost twenty years. She has won numerous awards including Castle Connolly Regional Top Doctor, Top Doctors New York Metro Area, New Beauty Top Beauty Doctor, and RealSelf Top Doctor. Learn More Fact checked by Isaac Winter Fact checked by Isaac Winter Isaac Winter is a fact-checker and writer for Real Simple, ensuring the accuracy of content published by rigorously researching content before publication and periodically when content needs to be updated. Highlights: Helped establish a food pantry in West Garfield Park as an AmeriCorps employee at Above and Beyond Family Recovery Center. Interviewed Heartland Alliance employees for oral history project conducted by the Lake Forest College History Department. Editorial Head of Lake Forest College's literary magazine, Tusitala, for two years. Our Fact-Checking Process There are certain ingredients that tend to echo in the world of beauty. And these days, it's rare to speak to a derm or walk down a skincare aisle without hearing or seeing something about the exfoliating, radiating glory that is glycolic acid. But what exactly is this magic molecule and does it live up to the hype? From how it works to how to incorporate it into your routine, read on for everything you need to know about this "holy grail" acid. What Is Glycolic Acid? Simply put, glycolic acid is a colorless, odorless, highly water-soluble molecule (or, more specifically, alpha-hydroxy acid) derived from sugarcane. "Of the alpha hydroxy acids, glycolic acid is the smallest molecule with the least complex chemical structure, which allows it to more easily penetrate the outer layers of the skin and get to work," explains Jeffrey Fromowitz, M.D., a board-certified dermatologist in Boca Raton, Florida. What Does Glycolic Acid Do? According to Dr. Fromowitz, glycolic acid works by aiding the dull and outer layers of the skin in exfoliation, making for brighter, healthier, and more hydrated skin underneath. "It dissolves the connections between the cells that make up the stratum corneum (the skin's outer layer) and increases skin cell turnover," he explains. As a product, glycolic acid can improve acne and help correct pigmentation problems. It's the star ingredient in Caudalie's Vinoperfect Brightening night cream formula. Also, one of the best toners for acne is The Ordinary Glycolic Acid 7% Toning Solution. Dr. Fromowitz points out there is also evidence that suggests regular use of glycolic acid can help improve fine lines and wrinkles. "As it penetrates into the skin's surface, it activates fibroblasts, which are the cells in the skin that produce collagen," he explains. Translation: It's an anti-aging powerhouse. How Often Should You Use Glycolic Acid? As for how to incorporate glycolic acid into your routine, Dr. Fromowitz suggests starting with a wash to reap the benefits, while limiting contact exposure. Glytone's exfoliating cleanser is a good face wash for acne. "Those with sensitive skin should start slowly, perhaps using a wash only a couple days a week and building up from there," he adds, noting that side effects can include redness, skin sensitivity, dryness, and itchiness. After a few weeks without irritation, you should be set to increase your frequency. "If daily use is tolerated well and you'd like to address other skin concerns, you can potentially add in a topical leave-on product that has glycolic acid as an ingredient." Can You Use Glycolic Acid With Retinol? As with most acids, Dr. Fromowitz cautions this is one area where it's not wise to play chemist. "You want to be careful not to combine AHA products with other acids or exfoliating products such as retinol, benzoyl peroxide, or salicylic acid. You should take care if you are treating acne with prescription products that contain Retin A." If you still have questions, it's best to seek advice from a trained professional (such as a dermatologist) who can assess your routine and prescribe the best products and formulas for you. 4 Skincare Ingredient Combinations You Should Try—and 3 to Avoid What Should You Look for in Glycolic Acid Products? Glycolic acid can be found in a range of products and formulas, from washes to serums to creams. "You want to look for well-formulated products from well-known brands," advises Dr. Fromowitz. "They will contain different percentages of active ingredients. Opt for lower concentrations in the beginning to allow the skin to adjust and minimize irritation. Lower concentrations also tend to be better for daily use." Dr. Fromowitz says you should keep your skin type and condition in mind. "If your skin is on the oily side, you might want to start with a serum. if your skin is on the dry side, a cream formula may be the best option." As for product picks, Dr. Fromowitz has become a fan of Glytone for well-formulated, affordable glycolic acid products. "The Skinmedica HA5 line also has good science behind the ingredients so the results are predictable and dependable," he recommends. Curious to give glycolic acid a try? Shop our favorite glycolic acid serums, toners, peels, and face washes below. Best Glycolic Acid Products for Skin 01 of 08 La Roche Posay B5 Glycolic Serum Ulta Buy on Amazon Dr. Devina Mehta, MD of Schweiger Dermatology in Hoboken, NJ says this is her “absolute favorite” glycolic acid serum. In addition to exfoliating acids, it also boasts B5 for hydration, a must-have for those who are prone to dryness. 02 of 08 Sunday Riley Good Genes Glycolic Acid Treatment Sunday Riley Buy on Sundayriley.com You’ve probably heard of Sunday Riley’s popular Good Genes Lactic Acid Treatment, which is a milder chemical exfoliant than this version, its glycolic acid sister. Dr. Mehta loves this serum — it’s a bit more potent to target buildup and discoloration but is balanced with prickly pear extract to soothe the skin. 03 of 08 Dermalogica Daily Glycolic Cleanser Sephora Buy on Sephora Another favorite of Mehta’s, if you’re looking to pare down your routine and skip the treatments, this cleanser comes packed with AHA to exfoliate and boost radiance all in the first step. Mehta says it's "safe to use daily" — just exercise caution when using around your eyes. 04 of 08 Sobel Skin 27% Glycolic Acid Facial Cleanser Sobel Skin $42, drsobelskinrx.com Recommended for all skin types, this gentle yet potent cleanser from Sobel Skin works hard at removing makeup, dirt, and oils, while exfoliating skin for improved texture. 05 of 08 The Ordinary Glycolic Acid 7% Toning Solution The Ordinary $10, ulta.com The Ordinary has made a name for itself by offering budget-friendly products with high-end results. This toner in particular was created to help improve congestion, while targeting signs of aging for a clean, youthful glow. 06 of 08 L'Oréal Revitalift 10% Pure Glycolic Acid Ulta $33, ulta.com This serum from L'Oreal is another accessible glycolic acid pick that punches above its price tag. Scoop up the plant-derived formula to help clear pores and improve your complexion (studies show brighter, smoother results in as little as one week). 07 of 08 Dr. Dennis Gross Alpha Beta Extra Strength Daily Peel Amazon $150, sephora.com Can't make it in for a professional peel, or perhaps you just want to extend your appointments? Opt for these beauty editor-loved pads from Dr. Dennis Gross, which have achieved cult status for their ability to rewind and redefine. 08 of 08 Drunk Elephant T.L.C. Framboos Glycolic Night Serum Drunk Elephant $134, sephora.com Turn back time as you snooze with this popular night serum from Drunk Elephant. While a custom AHA blend works to resurface, antioxidants rehydrate and soothe parched and irritated skin. Was this page helpful? Thanks for your feedback! Tell us why! Other Submit Sources Real Simple is committed to using high-quality, reputable sources, including peer-reviewed studies, to support the facts in our articles. Read our editorial guidelines to learn more about how we fact check our content for accuracy. Ravikumar B, R I, Pillai D. Efficacy of alpha and beta hydroxy acid chemical peels in postacne pigmentation: a double blinded, randomized, controlled trial. J Clin Aesthet Dermatol. 2022;15(1):48-52. Kubiak M, Mucha P, Rotsztejn H. Comparative study of 15% trichloroacetic acid peel combined with 70% glycolic acid and 35% trichloroacetic acid peel for the treatment of photodamaged facial skin in aging women. J Cosmet Dermatol. 2021;19(1):137-146. doi:10.1111/jocd.13171 Mbituyimana B, Mao L, Hu S, et al. Bacterial cellulose/glycolic acid/glycerol composite membrane as a system to deliver glycolic acid for anti-aging treatment. Journal of Bioresources and Bioproducts. 2021;6(2):129-141. doi:10.1016/j.jobab.2021.02.003